Microdosing, the practice of taking small amounts of psychedelic substances, has gained popularity in recent years as a potential treatment for depression. Here’s what you need to know about the latest studies:

The Studies

Several studies have been conducted in recent years to evaluate the effectiveness of microdosing for depression. A 2019 study found that microdosers reported improvements in mental health and mood that were generally consistent across the presence of mental health concerns, age, and gender(5). Another study conducted in 2021 found that adults who microdose psychedelics report health-related motivations and lower levels of anxiety and depression compared to non-microdosers(4). While the evidence is still limited, these studies suggest that microdosing may be a promising treatment option for depression.

The Potential Benefits

The potential benefits of microdosing for depression are significant. Many people who have tried microdosing report improvements in mood, creativity, concentration, productivity, and ability to empathize with others(3). These anecdotal reports are supported by lab studies of psilocybin and LSD microdoses, which tend to show improvements in mental health and well-being(1). Microdosing may also offer a more sustainable and accessible treatment option for depression than traditional antidepressants, which can have significant side effects and may not work for everyone(2).

The Risks

It’s important to note that there are still risks associated with the use of psychedelics, even in small doses. While microdosing is generally considered safe, it can still cause side effects such as anxiety, paranoia, and altered perceptions(6). It’s also important to use these substances under the guidance of a qualified medical professional who can monitor your response and ensure your safety.


The use of microdosing for depression is an exciting area of research, and the results of the studies conducted so far are promising. While there are still risks associated with the use of psychedelics, the potential benefits are significant, and may offer a new treatment option for those who are struggling with depression. If you’re interested in exploring the use of microdosing for your own well-being click here. We do advise consulting your physician if you intend to start microdosing to alleviate the effects of your depression.

1. https://www.brainfacts.org/diseases-and-disorders/mental-health/2020/how-microdosing-psychedelic-drugs-affects-mental-health-062420

2. https://www.nytimes.com/2022/02/28/well/mind/microdosing-psychedelics.html

3. https://www.health.harvard.edu/blog/the-popularity-of-microdosing-of-psychedelics-what-does-the-science-say-202209192819

4. https://www.nature.com/articles/s41598-021-01811-

5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753862/
6. https://healthyliferecovery.com/microdosing-psilocybin-the-pros-cons-and-unknowns/

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